Marquis Antiprotozoal Oral Paste

Marquis treats EPM. EPM is a parasitic disease that affects the brain, spinal cord, and nervous system in horses. It can cause mild signs of incoordination in some horses and can quickly make other horses so unstable they cannot get up. Marquis is a prescription medication that treats this incordination. Neurological signs include asymmetric incoordination (ataxia), weakness and spasticity, although they may mimic almost any neurological condition. Marquis is the best known medicine for this disease.

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Marquis (Ponazuril) Oral Paste - 127 gm

Marquis (Ponazuril) oral paste for the treatment of EPM (Equine Protozoal Myeloencephalitis). Each gram of Marquis delivers 150 mg of ponazuril. Comes in easy click-dose syringe. Each tube will treat a 1200 lb horse for 7 days.


Marquis Treats Horses With Epm

Marquis antiprotozoal oral paste
is a medication designed by Bayer Animal Health to treat horses that have been diagnosed with Equine Protozoal Myeloencephalitis, known as EPM for short. This is a truly difficult disease that can be very frustrating to deal with for veterinarians and horse owners alike. It is a parasite disease that affects the spinal cord, nervous system and brain of a horse. It begins to appear first as a slight lack of coordination or clumsiness, but it can quickly make a horse so unstable that it is unable to get up. Marquis is prescribed by vets as a way to treat this condition and it is the best known product of its type for this purpose.

A syringe of Marquis generally lasts for 7 days and because it is a paste, it is inserted via the syringe into the horse's mouth. Usually, your vet will recommend that you give your horse Marquis once per day for 28 days. It is important that your vet diagnose your horse as having EPM before you begin giving this treatment because EPM can mimic many other neurological conditions and you want to be certain that you are treating your horse appropriately.

The active ingredient in Marquis is called ponazuril and it acts against the parasites called S. neurona that cause EPM by crossing the blood-brain barrier to kill the parasite where it resides.

Early diagnosis is essential for this disease to be caught and treated quickly in order to get the best results for your horse's health. It is important not to ignore signs of clumsiness or leaning that can often indicate the presence of the parasites or other neurological conditions that your vet should have a look at. Because Bayer is a highly trusted name in vet medicine, you can know that Marquis has a high safety rating.

More Product Information:

Generic Name
Ponazuril (poh-naz-your-ill)

Bayer Animal Health

Brand Name(s)
Marquis Antiprotozoal Oral Paste

What is this medication used for
Marquis Antiprotozoal Oral Paste is indicated for the treatment of Equine Protozoal Myeloencephalitis (EPM) in horses caused by Sarcocystis neurona.

Marquis Antiprotozoal Oral Paste is available by prescription as ready-to-use syringes containing 127 grams of paste.

How this medication should be used
Marquis Antiprotozoal Oral Paste is FDA approved for use in horses only. Each oral syringe barrel contains enough paste to treat one 1,200 lb horse for 7 days at a dose rate of 2.27mg/lb. The plunger contains a dosage ring marked for horse weight from 600 to 1,200 lbs. The usual dose is 2.27mg/lb body weight once a day, by mouth, for 28 days.

What are the side effects
Side effects that can occur while using this medication include skin rash or hives, blisters on the nose and mouth, loose stools, mild colic and seizures.

What special precautions are there
This medication is for use in animals only. Not for human use. Do not use in horses intended for food. Prior to treatment EPM must be distinguished from other diseases that may cause ataxia in horses. The safe use of this product in horses used for breeding purposes, during pregnancy, or in lactating mares, has not been evaluated.

In the event of an overdose
Contact your veterinarian. Daily doses of up to 6 times the recommended dose primarily caused loose feces.

How should I store this product
Store at controlled room temperature (59º-86ºF).